Category: Biohacking (Page 1 of 2)

Phenibut Explained

Phenibut is a nootropic compound derived from a neurotransmitter known as GABA. This was achieved by a phenyl group to GABA, thus resulting in a compound called Phenibut (β-Phenyl-GABA). This insanely effective derivative is able to enter your brain and lower levels of anxiety and stress.

The intent was to create a chemical that would help users remain calm without sedating them with drugs like xanax. Phenibut is very potent and extremely effective in reducing stress and anxiety. It is commonly used as a potent sleep aid and has a pretty long half life as well.

The dark developmental history of this compound

I find This chemical extremely interesting due to its somewhat dark developmental history. The Soviet Union developed Phenibut in the 1960s for the Russian cosmonaut program.

They allegedly did this because the Soviets were having so many disastrous problems with their space program. Apparently there were too many manned rockets exploding and killing the cosmonauts upon entering the atmosphere. Many of the cosmonauts were terrified and on the brink of a mental breakdowns because they had a high chance of being blown up at work.

So the Soviets had their chemists take GABA and alter it with a phynl group in hopes of creating a drug that would calm their nerves so much that they would not care about anything.

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BPC157 Healing Peptide

BPC157 (also known as PL14736 and Body Protective Compound 157) is a pentadecapeptide. This means it has 15 amino acids with a sequence of 98 hydrogen, 62 carbon, 22 oxygen, and 16 nitrogen atoms. The peptide was banned by the World Anti-Doping Agency in 2022 under the S0 category of non-exempt substances.

BPC157 vs TB500

This healing peptide that is somewhat similar to TB-500. However, the main difference, in my opinion, is that TB-500 is systematic and BPC157 is more site specific.

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Post Surgery Healing Stack

I very recently underwent surgery to repair an inguinal hernia. This resulted in a 4 inch wide incision on my waistline and a very, very sore abdominal area. So, I thought ahead and did plenty of research to create a stack of both supplements and research chemicals to optimize my bodies healing abilities to result in faster recovery. This article will document everything I took during the process and the reasoning behind my taking it. I sincerely hope this information can prove helpful to you down the road.

Healing Peptides

TB500: SITE SPECIFIC HEALING PEPTIDE

I injected an entire vial of this but split it up into a several smaller shots around the perimeter of the surgery area. I then used the nasal spray version two times per day to maintain the peptide in my system. This amazing compound basically makes most tissues in the body heal faster and better. TB500 is a synthetic peptide of a naturally occurring protein in the body called thymosin beta-4. Thymosin beta-4 promotes healing by stimulating growth of new blood cells and muscle tissue. TB500 basically causes Thymosin beta-4 to accumulate in higher concentrations where tissue has been damaged. Animal experiments have shown that TB500 promotes migration/survival of cells, formation of blood vessels,  and lowering of pro-inflammatory cytokines.

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MOTS-c Metabolic Enhancement Peptide

MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial genome. Mitochondria play a critical role in the generation of metabolic energy and is responsible for most of the useful energy derived from the breakdown of carbohydrates and fatty acids, which is converted to ATP. 

The peptide has been researched extensively in the last few years due to its therapeutic potential, with no shortage of complex research documentation available for reading. Research to date has shown this peptide plays important roles in metabolism, weight regulation, exercise capacity, insulin sensitivity, longevity, anti aging, and even processes leading to disease states like osteoporosis.

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Noopept Nasal Spray Review

Noopept is an nootropic capable of enhancing brain or mental function. Noopept was created by Rita Ostrovskaya (Russian neuroscientist with a background in molecular biology) and patented by a Russian-based pharmaceutical company in 1996.

This nootropic is similar in action to the racetam-class nootropics but I consider it more of a neuropeptide as the primary compound responsible for its efficacy is a peptide called cycloprolylglycine (CPG).

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Theacrine Review: A Caffeine Alternative

For the past month I’ve been taking a deep dive into cognitive enhancing substances known as nootropics. One particular one that I found very interesting is a compound called Theacrine.  I have taken this compound every morning for three weeks to wean off caffeine in order to reset my tolerance.

This can be viewed, in my opinion, as a natural central nervous system stimulant and fantastic alternative to caffeine if used correctly.

Also known as 1,3,7,9-tetramethyluric acid, its a purine alkaloid found in Cupuaçu fruit and in Chinese tea known as kucha. It shows anti-inflammatory and analgesic effects and appears to affect adenosine signaling in a manner similar to caffeine.

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TAKING CARE OF OUR HEALTH BEFORE HEALTHCARE HAS TO TAKE CARE OF US

In medicine today, they’ve made a set of rules that are difficult to challenge because, ultimately, you do not have the medical freedom. When the founding fathers formed the constitution in 1776, they did so by having everything drafted, written, voted on, and approved.

One particular doctor Benjamin Rush wanted medical freedom and he was the surgeon general of the time. What Benjamin meant by ‘medical freedom’ was that all people could choose whatever medicine, type of care, or therapy they or their children wanted.

He also intended for every doctor to be able to practice any therapy or recommend any medicine they desired.

Dr. Benjamin Rush lost by 2 votes because George Washington was lobbied (yes even back then lobbyist were throwing dirty dollars at good men trying to buy their soul) and changed his vote.

Dr. Rush said, “George you’re going to regret this”!

You know what happened to poor George Washington? …He did pay for it a few years later.

One morning, he woke up with severe headaches, fever, and serious flu-like symptoms. So they did what they did in those days….BLOODLETTING!

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CJC1295 Explained and How To Use It

There are tons of different GH peptides, analogues, and sectretagogus out there and it can get pretty overwhelming as a new researcher trying to figure out what’s going to be best for YOUR lab experiment. However, CJC1295 has been the base of my GH Peptide research for years now.

What is CJC1295?

Exogenous GH use comes with several negative side effects in this particular Peptide was created to have all of the positives of Growth hormone while mitigating the not so favorable side effects that come with exogenous GH use. I’ve tried pretty much every GH analog/secretagogue/mimic/peptide that’s out there and I always come back to CJ1295.

CJC1295 is an analogue of growth hormone releasing hormone that was first developed in the 1980s. Basically, CJC1295 is the isolated amino chains 1 through 29 of the GHRH Peptide sequence.

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AOD9604 Weight Loss Peptide Review

AOD9604 is a Hexadecapeptide originally developed as an analogue of HGH with the express purpose of fighting fat. This peptide is actually a modified version of fragment 176-191, which is itself a small extracted sequence of HGH.

AOD9604 was originally developed as an anti-obesity drug. And this was due to its lipolytic fat burning properties. But surprisingly, this peptide has limited effects beyond fat burning.

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GW0742 Super Cardarine Explained

There are dozens of PPAR delta agonists in the pipeline which are in phase 2 and 3 clinical trials such as Elafibranor (GFT505) and Seladelpar (MBX-8025). However, There is a very interesting PPARβ/δ agonist called GW-0742, which is being dubbed as a ‘Super Cardarine’.

GW-0742 vs GW-501516

GW-0742 is a PPARβ/δ agonist that structurally looks like Cardarine(GW501516) but with one hydrogen atom replaced with a fluorine atom. 

From what I can tell is that it has all the positive traits of Cardarine with added benefits. 

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Testolone MENT Podcast

In this episode we are going to explore one of my favorite research compounds, Trestolone Acetate which is commonly known as MENT. Every time I post about this compound on the Instagram page, I get blown up with questions because its such a misunderstood compound. I organized this episode in a way that covers the scientific studies while also discussing first hand, real world experience.

Click any of the links below to listen to the show. You can CLICK HERE for the best source to buy Trestolone (MENT).

CLICK HERE to listen on Spotify

CLICK HERE to listen on Apple Podcast

CLICK HERE to Listen on Google Podcast

CLICK HERE to listen on Stitcher

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